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September 10, 2025Acta Biochimica Iranica

Evaluation of Leucomethylene Blue as a Protective Agent Against Acetaminophen-Induced Acute Lung Injury

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Authors

MEMajid EfatiSGSahar GhoflchiKKKhatereh Kharazmi

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Overview

Treatment with leucomethylene blue reduced oxidative and inflammatory damage in rats with acetaminophen-induced lung injury.

Key Points

  • LMB significantly diminished oxidative and inflammatory damage caused by acetaminophen toxicity.
  • Total antioxidant capacity and glutathione reductase activity were restored after LMB treatment.
  • LMB curbed the overproduction of pro-inflammatory cytokines in lung tissue, reducing damage.
  • Histopathological analysis confirmed that LMB improved pulmonary lesions and inflammation.

Cite This Study

Efati et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478d6dbhttps://doi.org/10.18502/abi.v3i2.19488
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