September 10, 2025Open Access

Barriers to and Enablers of Childhood Immunization Uptake in First Nations Communities in Canada: A Rapid Review of the Literature

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Discussion

Rapid review identifies barriers and enablers of vaccine uptake in First Nations, highlighting public health implications.

Vaccine uptake in First Nations communities is significantly impacted by various barriers, affecting public health.
Key barriers include misinformation, safety concerns, and scheduling conflicts, which hinder immunization rates.
Culturally safe care and community engagement are crucial enablers for improving childhood immunization uptake.
Public health interventions must address both systemic barriers and cultural considerations to enhance vaccine coverage.

Ndubuka et al. (2025) studied this question.

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