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September 10, 2025PeerJOpen Access

The platelet and coagulation function parameters in late pregnancy are associated with preeclampsia and its severity: a single-center retrospective study

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Authors

JZJindi ZhangJLJie LiuPWPei Wang

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Overview

Retrospective study shows platelet and coagulation function correlate with preeclampsia severity, indicating a useful risk model.

Key Points

  • MPV and TT are independent risk factors for preeclampsia, impacting its severity.
  • The risk model combining MPV and TT achieved an AUC of 0.827, reflecting good predictive ability.
  • Significant differences in platelet count and thrombin time were observed among groups with differing PE severities.
  • Multivariate analysis identified MPV and TT as key predictors for preeclampsia and its severity.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c23d3ab210217d6478d121https://doi.org/10.7717/peerj.19916
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet Parameters as an Indicator of Preeclampsia: A Single-Center Retrospective Study2025
  2. 2Changes in Blood Coagulation Parameters and Platelet Indices in Pregnancies with Gestational Hypertension and Preeclampsia2024
  3. 3Significance of platelet parameters in pre-eclampsia: A prospective cross-sectional study from a tertiary care center in North India2025
  4. 4Haemostatic Function and Predictive Values for Pre-Eclampsia Severity of Pregnant Women in a Rural West African Town2025
  5. 5Platelet Indices among Women with Pre-eclampsia attending at a Tertiary Care Hospital – A Case Control Study2025