Experimental study demonstrates that phytochemicals reduce hypertension-related biochemical markers in Wistar rats, suggesting potential for adjunct therapy.
Key Points
High-salt diet significantly increased systolic blood pressure to 158.4 mmHg and worsened cholesterol levels.
Treatment with Euphorbia hirta and Leptadenia hastata lowered blood pressure to 123–125 mmHg and improved cholesterol profiles effectively.
Salt-loading replicated biochemical abnormalities typically associated with hypertension in a reliable animal model.
Phytochemical extracts showed potential as adjunct therapies, comparable to conventional medication amlodipine.