Role of soluble fms-like tyrosine kinase-1/placental growth factor ratio as an early predictor of preeclampsia in pregnant women

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Discussion

Prospective cohort study evaluates sFlt-1/PlGF ratio for early prediction of preeclampsia, highlighting its diagnostic accuracy.

Elevated sFlt-1/PlGF ratio may predict preeclampsia earlier, suggesting improved patient outcomes.
ROC analysis indicated excellent accuracy with sensitivity of 96% and specificity of 97.6%, reinforcing its clinical relevance.
Longitudinal assessment of sFlt-1 and PlGF in 150 women showed significant differences pre- and post-diagnosis of preeclampsia.
Serial measurements of the sFlt-1/PlGF ratio could enhance screening and risk management in pregnant women.

Sangma et al. (2025) studied this question.

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