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September 10, 2025Pakistan Journal of Intensive Care Medicine

Microbial Etiology and Antibiotic Resistance in Surgical Site Infections: Implications for Observational Treatment

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Authors

MNMuhammad NomanLTLubna TariqWKWardah Khalid

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Overview

Observational study identified common pathogens and antibiotic resistance patterns in SSIs, highlighting AMR's impact.

Key Points

  • S. aureus and E. coli were the primary pathogens responsible for surgical site infections, indicating a significant challenge in treatment.
  • The study revealed that S. aureus showed high resistance to typical antibiotics, with resistance rates of 88% to penicillin and 82% to ampicillin.
  • Gram-negative organisms demonstrated alarming levels of antibiotic resistance, with 96.7% resistance to ampicillin, underscoring the need for effective alternative therapies.
  • Regular microbiological surveillance and culture-guided therapies are essential to enhance surgical site infection management and address rising antimicrobial resistance.

Cite This Study

Noman et al. (2025) studied this question.

synapsesocial.com/papers/68c23d3ab210217d6478c5b7https://doi.org/10.54112/pjicm.v5i02.146
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microbiological profile and antibiogram of surgical site infections2025
  2. 2IDENTIFICATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA IN POST-SURGICAL PATIENTS AND THEIR ANTIBIOTIC SENSITIVITY PATTERN2025
  3. 3Profile and impact of antimicrobial resistance related to surgical site infections after abdominal surgery in a resource-limited country: a prospective observational cohort study2025
  4. 4Antimicrobial susceptibility pattern of pathogens isolated from surgical wound infections in tertiary care hospitals of Pakistan2025 · 1 citations
  5. 5Common Organisms in Surgical Ward and Their Sensitivity: A Cross Sectional Study in a Tertiary Care Hospital, Bogura, Bangladesh2024