September 10, 2025Neurocritical CareOpen Access

Exploring the Upper Limits of Cerebral Perfusion Pressure in Pediatric Traumatic Brain Injury: A STARSHIP Analysis

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Observational analysis explores cerebral perfusion pressure in pediatric TBI patients, suggesting higher CPP may not worsen outcomes.

The association between high cerebral perfusion pressure and outcomes in pediatric TBI was evaluated.
No clear upper limit of autoregulation was noted, with PRx increasing only at CPP values above 100 mm Hg.
Using logistic regression, percentage time spent above CPP of 90 mm Hg showed a trend towards worse outcomes.
There was no difference in CPP between TBI patients with or without complications like acute respiratory distress syndrome.

Bögli et al. (2025) studied this question.

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September 10, 2025Neurocritical CareOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Observational analysis explores cerebral perfusion pressure in pediatric TBI patients, suggesting higher CPP may not worsen outcomes.

The association between high cerebral perfusion pressure and outcomes in pediatric TBI was evaluated.
No clear upper limit of autoregulation was noted, with PRx increasing only at CPP values above 100 mm Hg.
Using logistic regression, percentage time spent above CPP of 90 mm Hg showed a trend towards worse outcomes.
There was no difference in CPP between TBI patients with or without complications like acute respiratory distress syndrome.

Bögli et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark