September 10, 2025MedicineOpen Access

Complex causal association between immune cells and psoriatic arthritis: A bidirectional Mendelian randomization study

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Bidirectional mendelian randomization reveals key immunophenotypes affecting psoriatic arthritis risk, suggesting intricate immune cell interactions.

Eight immune traits were found to causally impact psoriatic arthritis, including several B cell traits.
The positive association was notably strong for T cell absolute cell, with an odds ratio of 1.70 indicating significant risk.
Using a bidirectional mendelian randomization method, the study assessed 731 immunological traits from genome-wide datasets.
These findings highlight the important role immune cells play in psoriatic arthritis, calling for further research in clinical settings.

Jia et al. (2025) studied this question.

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September 10, 2025MedicineOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Bidirectional mendelian randomization reveals key immunophenotypes affecting psoriatic arthritis risk, suggesting intricate immune cell interactions.

Eight immune traits were found to causally impact psoriatic arthritis, including several B cell traits.
The positive association was notably strong for T cell absolute cell, with an odds ratio of 1.70 indicating significant risk.
Using a bidirectional mendelian randomization method, the study assessed 731 immunological traits from genome-wide datasets.
These findings highlight the important role immune cells play in psoriatic arthritis, calling for further research in clinical settings.

Jia et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark