The Gut-Brain Axis in Autism Spectrum Disorder: Microbiota-Targeted Therapies and Neurobiological Insights

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This review highlights the link between gut microbiota and brain function in autism spectrum disorder, suggesting potential therapies.

Children with autism spectrum disorder show notable changes in gut microbiota and brain function.
Dysbiosis impacts neurotransmitter metabolism, particularly affecting GABA and serotonin levels.
Targeted therapies like probiotics and prebiotics may alleviate symptoms associated with autism spectrum disorder.
Further clinical research is crucial to establish safe applications of these microbiota-focused interventions.

Gajniak et al. (2025) studied this question.

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