September 10, 2025Open Access

GWAS for Periodontitis Phenotypes Using Multi-Ancestry All of Us Research Platform

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Significant genetic associations found in ancestry-specific GWAS for periodontitis phenotypes, revealing new insights.
The study cohort included 3,881 periodontitis patients and 10,760 controls from diverse ancestries, enhancing the analysis.
Multi-ancestry analysis confirmed critical loci such as LINC00294 and CLMN in the African population's periodontitis grade.
The findings suggest potential for integrating EHR and genomic data to inform dental health strategies and treatment.

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Genome-wide association study identifies key genetic associations in periodontitis, indicating potential for personalized treatments.

Sanders et al. (2025) studied this question.

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