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September 10, 2025Diseases of the Esophagus

Eno1 Lactylation as a Promising Predictive Biomarker and Therapeutic Target for Escc Metastasis

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Authors

HZHanlu ZhangWWWen-Ping WangYWYun Wang

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Overview

Lactylation shows promise as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma, suggesting new targets for treatment.

Key Points

  • Lactylation significantly influences metastasis in esophageal squamous cell carcinoma (ESCC).
  • In tissues, 91 lactylation sites showed increases in ESCC with lymph node metastasis, indicating a strong link.
  • Samples were analyzed from patients after radical surgery to investigate lactylation's role in ESCC metastasis.
  • Findings support lactylation's potential as a predictive biomarker and therapeutic target for ESCC.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478b88fhttps://doi.org/10.1093/dote/doaf061.142
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