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September 10, 2025Diseases of the Esophagus

Conversion Esophagectomy Following Immunochemotherapy in Unresectable Esophageal Squamous Cell Carcinoma: A Single-Center, Prospective Study

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Authors

GZGuoqing ZhangTMTeng MuJWJunya Wang

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Overview

This study evaluates conversion therapy outcomes in patients with unresectable esophageal squamous cell carcinoma, suggesting clinical efficacy in them.

Key Points

  • The conversion rate for unresectable esophageal squamous cell carcinoma reached 56%, indicating treatment potential.
  • R0 resection was achieved in 64.3% of patients undergoing thoraco-laparoscopic esophagectomy after conversion therapy.
  • Preoperative therapy included immunotherapy and chemotherapy, followed by surgery to assess clinical efficacy and safety.
  • With a median follow-up of 13.2 months, the findings support ongoing exploration of this treatment approach.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478b7e3https://doi.org/10.1093/dote/doaf061.276
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