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September 10, 2025Reproductive Female and Child HealthOpen Access

Paternal Influences on Offspring Bone, Muscle and Growth in Childhood and Adulthood: A Systematic Review

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Authors

MPMia A. PercivalKAKara B. AndersonJPJulie A. Pasco

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Overview

Systematic review identifies links between paternal lifestyle factors and offspring health outcomes in childhood and adulthood.

Key Points

  • Some paternal exposures, such as body mass index, correlate with musculoskeletal and growth measures in offspring.
  • Review analyzed findings from 290 studies, with 118 focusing on childhood and adulthood outcomes.
  • Systematic assessment utilized the Newcastle–Ottawa tool to evaluate risk of bias across studies.
  • Evidently, further robust research is essential to confirm associations of various paternal exposures.

Cite This Study

Percival et al. (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478b2cahttps://doi.org/10.1002/rfc2.70037
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exploring parental prenatal influences on child health: a multicohort study and data visualisation tool2025
  2. 2Associations Between Paternal Body Mass Index and Neurodevelopmental–Physical Outcomes in Small-for-Gestational-Age Children2025
  3. 3The association between parental BMI and offspring adiposity: A genetically informed analysis of trios2025
  4. 4Paternal prepubertal passive smoke exposure is related to impaired lung function trajectories from childhood to middle age in their offspring2025 · 4 citations
  5. 5Parental Cigarette Smoke Exposure and Its Impact on Offspring Reproductive Health: A Systematic Review of Maternal, Paternal, and Dual-Smoking Effects2025