Describing Pediatric Oncology Patients Enrolled in Phase 1 Clinical Trials

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Most pediatric oncology patients enrolled in Phase 1 trials received palliative care consultations.
Two-thirds of patients had pediatric palliative care support, but only 21% consulted before trial enrollment.
CNS tumors were the most common diagnosis among patients, comprising 44% of the cohort.
Median duration on study was 62 days, with a decrease in time for those participating in multiple trials.

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Retrospective analysis of 539 pediatric oncology patients in Phase 1 trials, highlighting the need for earlier palliative care involvement.

Cuviello et al. (2025) studied this question.

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Retrospective analysis of 539 pediatric oncology patients in Phase 1 trials, highlighting the need for earlier palliative care involvement.