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September 10, 2025Open Access

Targeting Cancer at its Core: Cellular and Genetic Approaches Via CAR-T Cell Therapy CAR-T Cell Therapy of Cancer

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Authors

BABandaru AashrithaAAAmbati AksharaNKNandini Kongara

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Overview

Review highlights CAR-T cell therapy's efficacy against hematologic malignancies, suggesting advances may broaden its application.

Key Points

  • CAR-T cell therapy induces remission in up to 80% of patients with hematologic malignancies, showcasing its significant efficacy.
  • The anti-CD19 CAR design, UCART19, demonstrates therapeutic potency in relapsed hematologic malignancies, underlining its effectiveness.
  • Innovations like gene editing and multi-antigen targeting enhance CAR-T cell therapy's potential, indicating prospects for broader applications.
  • Research explores additional surface antigens as therapeutic targets, with multiple clinical trials actively investigating their efficacy.

Cite This Study

Aashritha et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478a8cdhttps://doi.org/10.38124/ijisrt/25jun1371
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