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September 10, 2025JACC Case ReportsOpen Access

Emergency Heart Transplantation for Recurrent Infective Endocarditis With Irreparable Damage

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Authors

SHSuiqing HuangKFKangni FengJCJiantao Chen

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Overview

Emergency heart transplantation improves survival in a 61-year-old with recurrent infective endocarditis, suggesting a shift in treatment guidelines.

Key Points

  • Emergency heart transplantation resulted in survival with no infection recurrence in a patient with irreparable damage.
  • Successful transplantation required multidisciplinary consensus and timely organ availability, highlighting the need for specific protocols.
  • Prolonged antibiotics and immunosuppression were critical for achieving positive outcomes post-transplant.
  • Current guidelines on heart transplantation for active infective endocarditis may need updates based on recent evidence.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478a8a2https://doi.org/10.1016/j.jaccas.2025.105288
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Mitral Valve Replacement in Infective Endocarditis Complicated by Ischemic Stroke with Hemorrhagic Transformation: A Case Report2026
  2. 2Outcomes After Surgical Treatment of Infective Endocarditis with Destruction of the Cardiac Skeleton2025
  3. 3Simultaneous Cardiac Surgery for Infective Endocarditis and Liver Transplantation in End-Stage Liver Disease2025
  4. 4The role of surgery in contemporary infective endocarditis2025 · 1 citations
  5. 5Percutaneous Vegetectomy for Infective Endocarditis in a Nonsurgical Candidate2025