Folate status shows no relationship with vitamin B12 but reiterates the urgency for folate fortification in the UK

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Findings reveal no link between folate and vitamin B12 in young women, highlighting fortification necessity.

72.7% of women aged 16–50 showed low serum folate levels, risking neural tube defects.
The top decile had high mean serum folate of 43.9 nM/L, with holoTC levels averaging 119.2 pM/L.
No correlation between high folate status and negative vitamin B12 outcomes was identified.
Urgent action is needed for folate fortification to address deficiencies in young women.

Koulman et al. (2025) studied this question.

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