September 10, 2025Annals of HematologyOpen Access

Advancement of clinical practice in delivering CAR T-cell therapy: impact on healthcare resource utilization and comparison with autologous stem cell transplantation in patients with relapsed/refractory large B-cell lymphomas

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Authors

MFMartin FehrUniversity of St.Gallen MNMatthias NaegeleUniversity of St.Gallen MGMichael GreilingInstitute for Quality and Efficiency in Health Care

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Implication

Observational analysis evaluated healthcare resource utilization in patients receiving car t-cell therapy versus autologous stem cell transplantation, indicating significant efficiency improvements.

Key Points

Treatment with car t-cell therapy resulted in a 70%-75% shorter hospitalization compared to asct, enhancing patient care.
Healthcare resource utilization for car t-cell therapy was almost half that for asct, with 77% less personnel time needed.
Assessment utilizing ClipMed PPM software mapped 991 car t-cell therapy processes in 2023 and 1874 for asct, illustrating clinical practicality.
Improvements in lymphodepletion and management of adverse events facilitated a 30% reduction in hospitalization duration for car t-cell therapy.

Cite This Study

Fehr et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478a49b https://doi.org/10.1007/s00277-025-06564-y

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Implication

Observational analysis evaluated healthcare resource utilization in patients receiving car t-cell therapy versus autologous stem cell transplantation, indicating significant efficiency improvements.

Advancement of clinical practice in delivering CAR T-cell therapy: impact on healthcare resource utilization and comparison with autologous stem cell transplantation in patients with relapsed/refractory large B-cell lymphomas

Discussion

Member takes

Implication

Key Points

Cite This Study

Advancement of clinical practice in delivering CAR T-cell therapy: impact on healthcare resource utilization and comparison with autologous stem cell transplantation in patients with relapsed/refractory large B-cell lymphomas

Discussion

Member takes

Implication

Key Points

Cite This Study

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