Review of Retinopathy of Prematurity Management in the Anti‐VEGF Era: Evolving Global Paradigms, Persistent Challenges and Our AI‐Assisted Future

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Review highlights the impact of anti-VEGF and AI-assisted screening on ROP outcomes, suggesting pathways for improvement.

Management of retinopathy of prematurity has improved due to anti-VEGF treatments, but challenges remain.
Although pivotal trials underscore anti-VEGF's efficacy, long-term safety and effects on vision are still being studied.
Artificial intelligence and telemedicine may enhance ROP screening, especially in under-resourced areas, despite initial hurdles.
Persistent avascular retina in infants requires continuous monitoring for associated conditions like myopia and glaucoma.

Marra et al. (2025) studied this question.

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