September 10, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies

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Authors

AAAzal Hadi Al-MasoodyUniversity of Alkafeel MHMahshid HodjatTehran University of Medical Sciences TKTahereh Sadat Jafarzadeh KashiTehran University of Medical Sciences

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Implication

Systematic review surveyed in vitro and animal studies assessing hyaluronic acid's impact on dental pulp regeneration, suggesting promising potential.

Key Points

Most in vitro studies indicated a neutral effect of hyaluronic acid on cell proliferation, and a positive effect on dentinogenesis.
Animal studies predominantly reported increased dentine bridge formation when hyaluronic acid was used as a biomaterial.
Variability in study designs makes it challenging to draw definitive conclusions about hyaluronic acid's effectiveness.
Overall, studies suggest that hyaluronic acid holds promising potential for improving regenerative endodontic procedures.

Cite This Study

Al-Masoody et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d64789d57 https://doi.org/10.3389/fbioe.2025.1661188

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Implication

Systematic review surveyed in vitro and animal studies assessing hyaluronic acid's impact on dental pulp regeneration, suggesting promising potential.

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies

Discussion

Member takes

Implication

Key Points

Cite This Study

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies

Discussion

Member takes

Implication

Key Points

Cite This Study

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