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September 10, 2025Frontiers in Aging NeuroscienceOpen Access

The mediating role of depression on the association between physical activity and cognitive function among older adults

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Authors

HZHuanRui ZhangWTWen TianGQGuoxian Qi

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Overview

Analysis reveals that depression mediates cognitive function outcomes in older adults engaging in physical activity.

Key Points

  • Moderate to high-intensity recreation activity significantly improves cognitive function in older adults, reducing cognitive decline.
  • Depression mediates the relationship between moderate to high-intensity recreation activity and cognitive performance, influencing key cognitive tests.
  • Using weighted multivariable linear regression on 2,681 participants, the study investigates associations among physical activity, depression, and cognitive function.
  • The findings underscore the importance of addressing depression in interventions aimed at enhancing cognitive abilities in older adults.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d64789d3fhttps://doi.org/10.3389/fnagi.2025.1470256
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