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September 10, 2025

Characterization of hippocampal components of Danzhi Xiaoyao Formula based on HPLC-Q-TOF-MS/MS and network pharmacology and assessment of its therapeutic potential for nervous system diseases.

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Authors

WHWen-Qing HuHGHuiyuan GaoYLYang Li

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Overview

The study investigates the pharmacodynamic components of Danzhi Xiaoyao Formula for nervous system diseases, suggesting therapeutic pathways.

Key Points

  • Danzhi Xiaoyao Formula demonstrated potential in ameliorating nervous system diseases through signaling pathways.
  • Fifty-seven hippocampal components were identified, revealing connections to key targets like GSK3B and IL6.
  • Utilizing HPLC-Q-TOF-MS/MS, the study detailed pharmacological functions linked to neurodegenerative disorders.
  • The research highlights the formula's promise for treating conditions like Alzheimer's and Parkinson's, warranting further investigation.

Cite This Study

Hu et al. (2025) studied this question.

synapsesocial.com/papers/68c23c20b210217d64787ea8https://doi.org/10.19540/j.cnki.cjcmm.20250426.201
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