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September 10, 2025Open Access

Multi-Omics Profiling Reveals the Interplay Between Genomic Instability and Microenvironmental Remodeling in Pancreatic Neuroendocrine Tumors

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Authors

YWYin WanYZYingnan ZhangPPPhilip Agop Philip

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Overview

Review explores multi-omics roles in genomic instability and biomarkers in pancreatic neuroendocrine tumors, suggesting impacts on precision oncology.

Key Points

  • Multi-omics analysis improves understanding of genome-tumor microenvironment interactions in PNETs, revealing new insights.
  • It identifies co-evolutionary dynamics and potential biomarkers that may guide targeted therapies in pancreatic neuroendocrine tumors.
  • By integrating diverse omics data, the study enhances patient stratification for precision oncology efforts in genomic instability.
  • The findings support the development of innovative therapeutic strategies based on actionable vulnerabilities detected in tumors.

Cite This Study

Wan et al. (2025) studied this question.

synapsesocial.com/papers/68c23c20b210217d64787c45https://doi.org/10.20944/preprints202509.0362.v1
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