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September 10, 2025Frontiers in ImmunologyOpen Access

Association of systemic inflammatory factors with clinical outcomes in patients with autoimmune encephalitis at different clinical stages

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Authors

BJBo JinYDYiqun DuanWWWenxin Wu

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Overview

Retrospective analysis demonstrates systemic inflammatory factors affect disease severity and outcomes in autoimmune encephalitis, suggesting potential risks.

Key Points

  • Higher levels of systemic immune-inflammation index at admission were linked to severe disease outcomes.
  • Clinical scores indicating disease severity were positively correlated across multiple stages of assessment.
  • An elevated platelet-to-lymphocyte ratio at discharge was identified as an independent risk factor for severe disease.
  • A high neutrophil-to-platelet ratio was consistently associated with poor long-term prognosis in patients.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/68c23c20b210217d647878cehttps://doi.org/10.3389/fimmu.2025.1632690
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