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September 10, 2025Journal of Clinical MedicineOpen Access

Diagnostic Accuracy of Exercise Stress Testing, Stress Echocardiography, Myocardial Scintigraphy, and Cardiac Magnetic Resonance for Obstructive Coronary Artery Disease: Systematic Reviews and Meta-Analyses of 104 Studies Published from 1990 to 2025

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Authors

ASAndrea SonaglioniAPAlessio PolymeropoulosMBMassimo Baravelli

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Overview

Systematic reviews report diagnostic accuracy of exercise stress testing, myocardial scintigraphy, and cardiac magnetic resonance for coronary artery disease, showing varying sensitivities.

Key Points

  • Stress cardiac magnetic resonance exhibited the highest accuracy for detecting obstructive coronary artery disease.
  • Pooled sensitivities for coronary artery disease detection were 0.66 for exercise stress testing and 0.83 for stress cardiac magnetic resonance.
  • Systematic reviews compared diagnostic performances of exercise stress testing, stress echocardiography, myocardial scintigraphy, and cardiac magnetic resonance imaging.
  • Significant publication bias was detected; however, sensitivity analyses confirmed the robustness of pooled findings.

Cite This Study

Sonaglioni et al. (2025) studied this question.

synapsesocial.com/papers/68c23bd7b210217d64786d8ehttps://doi.org/10.3390/jcm14176238
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