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September 10, 2025PathogensOpen Access

Bioactive Compounds from Tithonia diversifolia Aerial Parts Against Eggs and Infective Larvae of the Parasitic Nematode Haemonchus contortus

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Authors

JCJorge Alberto Cortes-MoralesAOAgustín Olmedo-JuárezVTVictoria Michelle Tapia-Molina

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Overview

This study identifies bioactive compounds in Tithonia diversifolia, revealing their efficacy against Haemonchus contortus, suggesting sustainable alternatives for livestock health.

Key Points

  • The bioactive compounds from Tithonia diversifolia exhibited significant anthelmintic activity against Haemonchus contortus.
  • Egg hatching inhibition of 100% was achieved with the hydroalcoholic extract at 40 mg/mL and the ethyl acetate fraction at 4 mg/mL.
  • Phenolic compounds like flavonoids and hydroxycinnamic acids were identified, playing a crucial role in the anthelmintic efficacy.
  • These findings indicate potential sustainable alternatives for controlling gastrointestinal nematodes in small ruminants.

Cite This Study

Cortes-Morales et al. (2025) studied this question.

synapsesocial.com/papers/68c23bd7b210217d64786a9chttps://doi.org/10.3390/pathogens14090884
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Antioxidant and Anthelmintic Properties of <em>Tithonia diversifolia</em> Extracts Against Gastrointestinal Nematode Eggs Using <em>In Vitro</em> Assays2025
  2. 2Utilization of wild desert plant extracts for the <i>in vitro</i> control of gastrointestinal nematodes in cattle2025
  3. 3In vitro anthelminthic activities of Cucumis melo seeds against egg hatching, larval migration, and adult stage of Haemonchus contortus2025
  4. 4In vivo anthelmintic effects of polyphenol-rich extracts from the salt-tolerant species Cladium mariscus (L.) Pohl, 1809 and Limoniastrum monopetalum (L.) Boiss., 1848 against gastrointestinal parasitic nematodes in lambs2025
  5. 5Phenolic contents and antioxidant activity of Euphorbia hirta L hydroacetonic fractions2024