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September 10, 2025Connective Tissue Research

Identification of EMT-related subtype and a 9 genes signature predicts the prognosis in osteosarcoma

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Authors

FZFeng ZhouXXXuezheng XuYLYi Luo

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Overview

Gene expression analysis reveals two distinct EMT-related subtypes in osteosarcoma, suggesting implications for prognosis and immune features.

Key Points

  • The study identified two distinct osteosarcoma subtypes with significant differences in immune characteristics.
  • A prognostic risk model based on nine genes demonstrated high predictive accuracy for patient outcomes.
  • Cox regression analysis highlighted four independent prognostic factors linked to osteosarcoma prognosis.
  • Utilizing the TARGET database allowed for comprehensive gene expression and clinical data assessment in osteosarcoma patients.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68c23bd7b210217d647868bdhttps://doi.org/10.1080/03008207.2025.2554842
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