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September 10, 2025Open Access

Comparative Evaluation of High Vs Low Ovarian Stimulation Doses in PCOS Patients: Impact on ICSI Outcomes

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Authors

HKHesham Ahmed KadryMMMohamed El MahdyOZOmar Zakaria

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Implication

Randomized trial compares high and low ovarian stimulation doses in patients with PCOS, showing significant differences in ICSI outcomes.

Key Points

  • High ovarian stimulation led to higher fertilization and pregnancy rates compared to low stimulation.
  • The high stimulation group had statistically lower days of stimulation and higher numbers of oocytes retrieved.
  • Controlled ovarian stimulation using high doses may optimize outcomes for non-obese PCOS women.
  • The study revealed no additional risk of ovarian hyperstimulation syndrome with the high stimulation method.

Cite This Study

Kadry et al. (2025) studied this question.

synapsesocial.com/papers/68c23bd7b210217d647861a8https://doi.org/10.21203/rs.3.rs-6925389/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Pretreatment with Oral Contraceptive Pills on Intracytoplasmic Sperm Injection Outcome in Females with Polycystic Ovary Syndrome2025
  2. 2Association of blood progesterone levels on trigger day and low oocyte retrieval in cases with polycystic ovary syndrome undergoing in-vitro fertilization: A prospective cohort study2025
  3. 3Efficacy of sequential letrozole and gonadotropin therapy for ovulation induction in women with polycystic ovary syndrome: a systematic review and meta-analysis2025
  4. 4The management of slow ovarian response in PCOS patients and its impact on clinical pregnancy outcomes2025
  5. 5Successful Pregnancy in a PCOS Patient with Elevated Basal Luteinizing Hormone and Repeated Ovulation Induction Failures: A Case Report2025