Retrospective study compared survival in patients with esophageal squamous cell cancer, suggesting adjuvant therapies for high-risk individuals.
Key Points
Patients with invasive cancer length ≤ 10 mm had significantly shorter overall survival and disease-free survival, indicating a high-risk factor.
Kaplan‒Meier analysis showed a significant survival difference (OS, P < 0.01; DFS, P < 0.001) between those receiving radical surgery and the follow-up group.
The study reinforced that chemoradiotherapy is beneficial for high-risk patients after endoscopic resection, while low-risk patients do not derive the same benefit.
It recommends against radical surgery for any patient, highlighting the importance of risk stratification for treatment decisions.