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September 10, 2025Parasitology ResearchOpen Access

The potential relationship between Toxocara canis infection and epilepsy in a rat model

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Authors

ASAmina M. SalamaDEDina I. ElgendyRERasha A. Elmahy

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Overview

This study explores the association between neurotoxocariasis and epilepsy in a rat model, revealing significant neurochemical changes.

Key Points

  • Rats infected with toxocara canis exhibited motor seizures, indicating a potential link to epilepsy.
  • Histopathological changes in the brain were observed, linked to increased inflammatory markers and oxidative stress.
  • Biochemical analysis showed disturbances in neurotransmitter levels, underscoring the infection's impact on brain function.
  • The findings suggest that toxocara canis may contribute to epilepsy via neuroinflammatory processes.

Cite This Study

Salama et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64785eachttps://doi.org/10.1007/s00436-025-08528-7
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Also Consider

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  4. 4Cellular immunity indicators of dogs with epilepsy with different viral and toxoplasmosis antigenic load2025
  5. 5Long-Term Neuroimaging Findings in a Murine Model of Human Extraparenchymal Neurocysticercosis2025