September 10, 2025Open Access

Differential Impact of Fracture Type and Age on In-Hospital Mortality and Costs: A Retrospective Cohort Analysis of 352,269 Fragility Fracture Hospitalizations in Brazil

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Discussion

Retrospective cohort analysis shows age and fracture type affect in-hospital mortality and costs significantly.

In-hospital mortality was 2.69%, with proximal femur fractures showing the highest rate at 4.96%.
Median hospitalization costs for non-survivors were significantly higher at R 1,876.18 compared to R 1,045.18 for survivors.
Age significantly interacted with fracture type, increasing mortality odds by 1.26% for proximal femur and 0.76% for forearm/wrist fractures.
These findings suggest targeted healthcare policies are necessary to address the economic burden of fragility fractures.

Pereira et al. (2025) studied this question.

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