Retrospective analysis identifies D-Dimer, GSP, and HbA1c as strong predictors of macrosomia in gestational diabetes, suggesting improved screening methods.
Key Points
The macrosomia group showed significantly elevated serum levels of D-Dimer, GSP, and HbA1c compared to the normal group, highlighting their predictive value.
High combined AUC of 0.9241 indicates that D-D, GSP, and HbA1c together provide superior diagnostic accuracy for macrosomia in pregnancies with GDM.
Multivariate regression analysis confirmed that D-Dimer, GSP, and HbA1c were significantly associated with macrosomia incidence, even after BMI adjustments.
The assessment of these biomarkers allows for early identification of high-risk pregnancies, potentially improving maternal and neonatal outcomes.