September 10, 2025

The Effects of Prebiotic Dietary Fibers, Probiotics, and Synbiotics on Gut Permeability and Immunity: A Systematic Review.

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Prebiotic, probiotic, and synbiotic supplementation potentially affects intestinal permeability based on serum zonulin levels.
The review included 36 studies, with varying participant numbers affected by dietary interventions enhancing gut health.
Systematic analysis across multiple databases evaluated clinical trials focusing on gut microbiota and inflammatory markers.
Inconsistent results on gut health metrics highlight the need for more robust studies for reliable dietary recommendations.

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Systematic review evaluates effects on intestinal permeability and gut microbiota, suggesting mixed results.

Maghsoumi‐Norouzabad et al. (2025) studied this question.

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