September 10, 2025

[Effects and mechanism of tannic acid/magnesium nanocomplex on wound healing in rats with full-thickness scald].

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MgTA nanocomplex significantly improved wound healing rates at post-injury days 7 and 14 compared to the control group.
Significant reductions in M1 macrophage markers and increases in M2 markers were observed with higher concentrations of MgTA nanocomplex in RAW 264.7 cells.
The expression levels of lactate dehydrogenase indicators significantly increased with MgTA treatment in macrophages, enhancing energy metabolism.
Inflammatory factor TNF-α levels significantly decreased in composite hydrogel group compared to control, indicating reduced inflammation post-treatment.

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Experimental study shows improved wound healing rates in rats treated with magnesium nanocomplex, suggesting enhanced macrophage polarization.

Li et al. (2025) studied this question.

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Experimental study shows improved wound healing rates in rats treated with magnesium nanocomplex, suggesting enhanced macrophage polarization.