September 10, 2025

Fertility Preservation in Pediatric Oncology: A 10-Year Single-Center Experience in Northern Spain.

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Retrospective analysis shows increasing access to fertility preservation in pediatric oncology, highlighting gonadotoxicity risks.

Increased access to fertility preservation techniques reflects growing awareness and uptake by clinicians.
Weak agreement was found between gonadotoxicity risk classifications, complicating patient identification for fertility preservation.
Long-term follow-up in survivors identified ovarian insufficiency in 1.2% and early azoospermia in 0.7% of patients.
Hematopoietic stem cell transplantation emerged as a significant predictor of early infertility in pediatric cancer patients.

Carmona-Núñez et al. (2025) studied this question.

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