September 10, 2025

[Electroacupuncture of "Tianshu" (ST25) alleviates ulcerative colitis by activating sacral parasympathetic postganglionic neurons of the pelvic ganglion in mice].

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Electroacupuncture significantly reduces inflammatory response and improves histopathological scores in ulcerative colitis mice, enhancing healing.
Body weight loss in model mice decreased significantly with electroacupuncture, by showing a reduction in weight loss compared to the model group.
Assessment utilized immunofluorescence staining and high-performance liquid chromatography to measure neurotransmitter levels in colon tissues.
Results indicate potential mechanisms of electroacupuncture targeting parasympathetic postganglionic neurons, while effects on sympathetic neurons remain inconclusive.

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Observational analysis demonstrates the role of sacral parasympathetic activation in ulcerative colitis, indicating EA's potential benefits.

Luo et al. (2025) studied this question.

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Observational analysis demonstrates the role of sacral parasympathetic activation in ulcerative colitis, indicating EA's potential benefits.