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September 10, 2025

Effects of different exercise prescription parameters on metabolic and inflammatory biomarkers in cancer patients: a systematic review, meta-analysis, and meta-regression.

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Authors

JWJingyu WangYHYuxuan HeZWZiqian Wang

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Overview

Systematic review and meta-analysis reveal exercise shows significant benefits for biomarkers in cancer, highlighting dose-response relationships.

Key Points

  • Exercise significantly reduced insulin levels in cancer patients, indicating a modest but meaningful benefit.
  • Pooling of data from 74 trials assessed through meta-analysis showed exercise impacts metabolic and inflammatory biomarkers.
  • Robust Variance Estimation methods were used to examine the influence of exercise parameters on biomarkers in cancer patients.
  • High-intensity aerobic exercise emerged as essential for improving IL-6 and adiponectin, suggesting important modulation mechanisms.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64784fb3https://doi.org/10.3389/fimmu.2025.1663560
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Exercise on Immune System Markers in Cancer Patients and Survivors: A Systematic Review2025
  2. 2Effects of Exercise Interventions on Breast Cancer Patients During Adjuvant Therapy: A Systematic Review and Meta-Analysis2025
  3. 3Unveiling the perfect workout: exercise modalities and dosages to ameliorate adipokine dysregulation in individuals with overweight and obesity: a systematic review with pairwise, network, and dose–response meta-analyses2025
  4. 4Effect of Different Exercise Modalities on Inflammatory Markers in Individuals with Depressive Disorder: A Systematic Review and Meta-Analysis2025
  5. 5Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis.2025