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September 10, 2025

Wuling powder ameliorates diarrhea-predominant irritable bowel syndrome in mice by modulating gut mucosal microbiota and alleviating intestinal inflammation.

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Authors

QTQianghong TianDYDonglin YuJSJunxi Shen

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Overview

Experimental study shows Wuling powder reduces inflammation and regulates microbiota in IBS-D mice, suggesting its potential for therapy.

Key Points

  • Wuling powder significantly reduces TNF-α and IL-6 levels in mice with irritable bowel syndrome.
  • Compared to the model control group, the treatment group exhibits increased MFGE8 and restored microbiota diversity.
  • 16S rRNA high-throughput sequencing reveals a connection between microbiota changes and inflammation levels.
  • Findings support the potential of Wuling powder in clinical applications for managing irritable bowel syndrome.

Cite This Study

Tian et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64784eb7https://doi.org/10.3389/fcimb.2025.1652186
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