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September 10, 2025PLoS neglected tropical diseasesOpen Access

The relationship between expelled eggs, morbidity and age in a Schistosoma mansoni endemic setting in Uganda: Implications for current elimination policies

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Authors

RLRivka LimRLRuhi LahotiJCJessica Clark

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Overview

Observational analysis reveals age predicts morbidity in Schistosoma mansoni endemic regions, highlighting current policy gaps.

Key Points

  • Age was a consistent predictor of morbidity, with pre-school-aged children showing the highest burden of conditions.
  • Prevalence of liver parenchyma image pattern and portal vein dilation was observed at 9% and 34%, respectively.
  • Current infection intensity metrics may be inadequate for assessing schistosomiasis morbidity, urging policy re-evaluation.
  • Positive malaria status correlated with both portal vein dilation and anaemia, emphasizing co-infection effects.

Cite This Study

Lim et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d64784d20https://doi.org/10.1371/journal.pntd.0012750
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Also Consider

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  1. 1Schistosomiasis amongst adolescent boys in non-lakeshore southern Malawi: Investigating local risk-factors within a nested community-based cross-sectional survey2025
  2. 2Association between Schistosoma mansoni infection and fecal occult blood in schoolchildren in Mbita, Suba North Sub-County, western Kenya2025
  3. 3Prevalence of schistosome infection among children under two years of age: a brief report from medium-to-high endemic regions of Schistosoma mansoni in Madagascar2025 · 1 citations
  4. 4Distribution of schistosomes and soil-transmitted helminth infections and their association with growth and nutritional status of School-aged children of the Matta health area in the West region of Cameroon2025 · 3 citations
  5. 5Influence of Schistosoma mansoni infection on faecal calprotectin in the context of HIV, hepatitis B, and malaria co-infections2025