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September 10, 2025Theoretical and Natural ScienceOpen Access

Exploration of the Mechanism of Action of Immune Checkpoint Inhibitors and Their Advancements in Cancer Immunotherapy

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QWQian Wu

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Overview

Observational analysis demonstrates improved overall survival with immune checkpoint inhibitors in cancer, highlighting ongoing challenges in patient response variability.

Key Points

  • Immune checkpoint inhibitors significantly restore antitumor immune responses, showing durable efficacy in cancer treatments.
  • Approximately 20-40% of patients achieve sustained remission with immune checkpoint inhibitors, while 50-70% experience adverse events.
  • Clinical challenges arise from the limited predictive accuracy of biomarkers like programmed cell death-ligand 1 across different cancer types.
  • Future research must focus on multi-omics biomarkers and combination regimens to enhance immunotherapy precision.

Cite This Study

Qian Wu (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d6478478ahttps://doi.org/10.54254/2753-8818/2025.pj26468
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