September 10, 2025Journal of Neonatal SurgeryOpen Access

Single-cell RNA Sequencing of Cardiomyocytes in Early Ischemic Heart Disease

View Full Paper

Ask AI

Bookmark

Distinct transcriptional changes in cardiomyocytes were observed, indicating stress responses to early ischemia.
Upregulation of stress-related genes like NPPB and HIF1A suggests adaptation mechanisms in early IHD.
Pathway analysis highlighted the activation of inflammatory processes, pointing to altered cellular functions in cardiomyocytes.
These findings may reveal potential biomarkers or therapeutic targets for progressing myocardial disease.

Discussion

No takes yet. Share an insight, caveat, or question.

Observational analysis identified transcriptional changes in cardiomyocytes in early IHD, suggesting stress-response and hypoxia adaptation.

Rauf et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Observational analysis identified transcriptional changes in cardiomyocytes in early IHD, suggesting stress-response and hypoxia adaptation.