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September 10, 2025Open Access

Screening for Rheumatoid Arthritis-Associated Interstitial Lung Disease Using Low-Dose CT: An Emerging Approach — An Observational Prospective Case-Control Study

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Authors

KFKinga FritschSemmelweis UniversityJMJudit MajnikSemmelweis UniversityMTMichal TomčíkCharles University

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Implication

Observational study assesses low-dose CT's diagnostic performance for interstitial lung disease and associated risk factors.

Key Points

  • LD PCD-CT identified interstitial lung disease in 35% of rheumatoid arthritis patients, enhancing early detection.
  • Sensitivity of LD PCD-CT exceeds clinical assessments (44%) and pulmonary function tests (22%) for identifying abnormalities.
  • Prospective case-control study conducted with 492 RA patients, evaluating multiple screening modalities for ILD.
  • Incorporating low-dose CT into screening protocols may improve early diagnosis and patient management for RA-ILD.

Cite This Study

Fritsch et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d6478444ehttps://doi.org/10.21203/rs.3.rs-7204385/v1
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