Association between nausea and vomiting during pregnancy and adverse pregnancy outcomes: findings from the nuMoM2b study

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Observational analysis reveals associations between nausea severity and adverse outcomes, suggesting gestational weight gain as a key factor.

One visit with medium-to-severe nausea and vomiting of pregnancy was linked to a modest birth weight reduction of 41.4 g.
Inadequate gestational weight gain significantly reduces gestational age by 0.53 weeks and increases the risk of low birth weight.
Multivariable regression models adjusted for sociodemographic covariates were employed to analyze outcomes in 8396 women.
Nutritional support and symptom management are critical for women experiencing moderate-to-severe nausea and vomiting during pregnancy.

Hsieh et al. (2025) studied this question.

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Observational analysis reveals associations between nausea severity and adverse outcomes, suggesting gestational weight gain as a key factor.