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September 10, 2025Therapeutic Advances in Chronic DiseaseOpen Access

Joint effects of prognostic nutritional index and skeletal muscle index on prognosis of decompensated cirrhosis: a retrospective cohort study

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Authors

SYShuangzhe YaoBPBinbin PengJLJia Li

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Overview

Retrospective cohort study shows combined PNI and SMI effectively identifies malnutrition in cirrhosis, suggesting better prognosis assessment.

Key Points

  • Combining the PNI and SMI improves detection of malnutrition and may lead to better outcomes in patients with cirrhosis.
  • The prevalence of malnutrition in the cohort varied: 26.72% identified by PNI and 56.11% by PNI-SMI, with high relevance for interventions.
  • Cox regression analysis revealed all malnutrition criteria predict 1-year mortality, with hazard ratios indicating significant risks.
  • Overall, the PNI and SMI offer a practical, moderately accurate approach to nutritional assessment, enhancing the use of GLIM criteria.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d64783f0dhttps://doi.org/10.1177/20406223251369763
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nutritional Status and Hospitalizations in Cirrhotic Patients: A 1-Year Follow-Up Study Based on the Prognostic Nutritional Index2025
  2. 2Prognostic value of prognostic nutritional index in patients undergoing surgery for gastric cancer2025 · 4 citations
  3. 3The Prognostic Nutritional Index (PNI) Is a Powerful Biomarker for Predicting Clinical Outcome in Gastrointestinal Emergency Patients: A Comprehensive Analysis from Diagnosis to Outcome2025 · 7 citations
  4. 4Prognostic nutritional index is a better inflammation based prognostic marker in elderly patients with hepatocellular carcinoma after surgery2025 · 5 citations
  5. 5The relationship between prognostic nutritional index and its components (albumin and lymphocyte count) and all-cause mortality in lung cancer patients: a hospital-based study with database external validation2025