Isolation and evaluation of a new hyaluronidase from a non-pathogenic bacterium, supporting regulatory safety for industrial applications.
Key Points
The novel hyaluronidase from Paenibacillus residui exhibited no significant toxicity, demonstrating its potential as a biocatalyst.
Characterization revealed a molecular weight of 170 kDa with optimal activity at pH 8.0–9.0 and 50 °C, showing its effectiveness for industrial applications.
Safety evaluations confirmed the absence of virulence factors and no hemolytic activity, enhancing its regulatory acceptance.
Results support the use of BSSK58 hyaluronidase in pharmaceuticals, cosmetics, and functional foods, adhering to safety and regulatory standards.