September 10, 2025PharmaceuticalsOpen Access

Present and Future Perspectives in the Treatment of Liver Fibrosis

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Current therapies for liver fibrosis primarily slow disease progression but rarely reverse it, signaling a need for more effective treatments.
Pharmacological interventions, including bile acids and FXR agonists, have shown promise but often come with limitations or side effects.
Microbiota-adjusting therapies such as probiotics and antibiotics could modulate liver health, requiring further clinical validation for efficacy.
Emerging therapies like gene editing and immunotherapy could redefine treatment landscapes for liver fibrosis, highlighting the importance of ongoing research.

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This review highlights antifibrotic strategies and innovative treatments for liver fibrosis, indicating significant future directions in therapy.

Cerrito et al. (2025) studied this question.

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This review highlights antifibrotic strategies and innovative treatments for liver fibrosis, indicating significant future directions in therapy.