September 10, 2025NatureOpen Access

A brain-wide map of neural activity during complex behaviour

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Comprehensive recordings show how neural activity encodes sensory inputs and decisions in mice, suggesting interactions across brain regions.

Neural activity correlated with motor action throughout the brain, indicating widespread processing.
Data from 621,733 neurons recorded using 699 Neuropixels probes highlight decision-making dynamics.
Recording involved 139 mice across 12 laboratories, emphasizing collaborative neuroscience efforts.
Initial appraisal reveals how visual stimuli and rewards influence brain activity patterns.

Meshulam et al. (2025) studied this question.

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Comprehensive recordings show how neural activity encodes sensory inputs and decisions in mice, suggesting interactions across brain regions.