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September 10, 2025JAMA Cardiology

Prevalence and Clinical Implications of Sleep Apnea in Hypertrophic Cardiomyopathy

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Authors

SKShahid KarimAsia UniversityCCC. Anwar A. ChahalSt Bartholomew's HospitalSVShreyas VenkataramanWashington University in St. Louis

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Implication

Prospective cohort study found high sleep apnea rates in hypertrophic cardiomyopathy patients, indicating significant cardiovascular implications.

Key Points

  • Sleep apnea is highly prevalent in hypertrophic cardiomyopathy patients, affecting 59.1% of participants.
  • Sleep apnea diagnosis correlates with higher left ventricular mass index and elevated troponin-T levels, indicating myocardial stress.
  • Study utilized polysomnography for sleep apnea classification and assessed echocardiographic parameters for heart function.
  • Undiagnosed sleep apnea may worsen symptoms and contribute to heart issues, necessitating treatment trials in affected patients.

Cite This Study

Karim et al. (2025) studied this question.

synapsesocial.com/papers/68c23b08b210217d64782fe3https://doi.org/10.1001/jamacardio.2025.2877
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy2019 · 166 citations