September 10, 2025PLoS ONEOpen Access

Transplacental transfer of maternal SARS-CoV-2 antibodies in dichorionic and monochorionic twin pregnancies

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Maternal and cord anti-Spike antibody concentrations were lower in twin pregnancies compared to singleton pregnancies.
The study included 362 singleton and 36 twin pregnancies, highlighting significant antibody transfer differences.
Transplacental transfer inefficiency was noted in monochorionic pregnancies, emphasizing unique challenges.
Further exploration is essential to understand impaired transplacental IgG transfer in at-risk pregnancies.

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Cohort study finds lower maternal SARS-CoV-2 antibody levels in twin pregnancies, suggesting differences in antibody transfer efficiency.

Stolarczuk et al. (2025) studied this question.

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