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September 10, 2025Drug Design Development and TherapyOpen Access

Effect of Neoadjuvant Immunochemotherapy on Postoperative Pulmonary Complications for Locally Advanced Esophageal Cancer: A Propensity Score Matching Cohort Study

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Authors

WDWei DuXQXi QiaoJYJi‐Fang Yao

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Overview

Cohort study reveals increased postoperative pulmonary complications after neoadjuvant immunochemotherapy in patients with locally advanced esophageal cancer.

Key Points

  • Patients receiving neoadjuvant immunochemotherapy had a significantly higher rate of postoperative pulmonary complications.
  • PPCs occurred in 46.2% of the NICT group compared to 26.4% in the control group, indicating a notable increase.
  • The study utilized propensity score matching to balance characteristics and conditional logistic regression for analysis.
  • These findings suggest that NICT may pose pulmonary risks that need to be considered in treatment decisions.

Cite This Study

Du et al. (2025) studied this question.

synapsesocial.com/papers/68c23b08b210217d64782ea6https://doi.org/10.2147/dddt.s537794
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